Extractive composition and bioactivity of Uncaria acida and Uncaria glabrata wood

Authors

  • Masendra Masendra Universitas Gadjah Mada
  • Brandon Aristo Verick Purba Universitas Gadjah Mada
  • Lies Indrayanti Universitas Palangkaraya, Indonesia
  • Ganis Lukmandaru Universitas Gadjah Mada

DOI:

https://doi.org/10.15287/afr.2020.1979

Keywords:

Wood extractives, Antifungi, Bajakah, Phytomedicine, Polyphenols

Abstract

Uncaria acida (red bajakah) and Uncaria glabrata (white bajakah) belong to the liana woody species. Both are naturally cultivated in Indonesia, particularly in Kalimantan (Borneo) island. This study, aims to investigate the extractive composition of U. acida and U. glabrata wood considering that extracts from different lianas usually are used as anticancer drugs (breast cancer). The phenolic, alkaloid, and saponin contents were measured by colorimetric and GC-MS methods, while the antioxidant, antifungal, and cytotoxicity were investigated using DPPH, Phanerodontia chrysosporium (white-rot), and brine shrimp lethality tests, respectively. The results showed that the total tannins, phenols, and saponins in U. acida were higher compared to U. glabrata, while the total flavonoids, alkaloids, polysaccharides, and antioxidant activity was lower. The GC-MS analysis indicated the presence of aromatic compounds, fatty acids, and triterpenoids in both species. High concentration of phenols, alkaloids, saponins, fatty acids, and steroids are known to provide support in terms of antioxidant, cytotoxicity, and antifungal activities.

Author Biographies

Masendra Masendra, Universitas Gadjah Mada

Department of Forest Products Technology, Faculty of Forestry, Universitas Gadjah MadaDepartment of Bioresources Technology and Veterinary, Vocational College, Universitas Gadjah Mada

Brandon Aristo Verick Purba, Universitas Gadjah Mada

Department of Forest Products Technology, Faculty of Forestry, Universitas Gadjah Mada

Lies Indrayanti, Universitas Palangkaraya, Indonesia

Department of Forestry, Faculty of Agriculture, Universitas Palangkaraya

Ganis Lukmandaru, Universitas Gadjah Mada

Department of Forest Products Technology, Faculty of Forestry, Universitas Gadjah Mada

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2021-12-25

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Vol. 64 No. 2 (2021)

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Research article

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